Abstract Background Melatonin (MEL) is a powerful antioxidant molecule with anti-androgenic property.A microemulsion (ME) system loaded with MEL was designed for treatment of androgenic alopecia.Pseudo-ternary phase diagram was constructed, and ME formulae were developed using coconut oil, Tween 80 and PEG 400.In the present study, MEL ME was chara
Estimating time-varying graphs, i.e., a set of graphs in which one graph represents the relationship among nodes in a certain time slot, from observed data is a crucial problem in signal processing, machine learning, and Speaker Grille data mining.Although many existing methods only estimate graphs with a single temporal resolution, the actual grap
Osteoarthritis (OA) is one of the most prevalent musculoskeletal disorders globally, and treating OA remains a significant challenge.Currently, pharmacological treatments primarily aim to alleviate the OA symptoms associated with inflammation and pain, and no disease-modifying therapies are available to delay OA development and progression.Reactive
For sample return missions from deep space, a thin aeroshell capsule was proposed aimed at mitigating the aerodynamic heating during its reentry into the earth's atmosphere.The functional requirements of the capsule mandate that it aerodynamically decelerate sufficiently and land in the appropriate attitude without a parachute.To evaluate its